Job: Cell Biologist, Bioassay Screening, Loxo Oncology, Boulder, CO

General Information

Job title:
Cell Biologist, Bioassay Screening
Job location:
Boulder, CO 80202 United States

Requisition code:
Date posted:
Job type:

Career path:

Scientific Discipline:

Job Description

The Cell Biologist will be responsible for identifying, developing, and performing robust, reproducible cell assays to support drug discovery and development in a team environment. The Cell Biologists will provide hands-on compound testing to support the small molecule drug discovery oncology pipeline. The scientist fulfilling this position will be responsible for characterizing the effects of small molecule compounds on specific protein targets in cells using multiple plate-based assay formats examples include HTRF, ELISA, In-Cell Western, Mesoscale, and proliferation. A strong background in experimental curve-fitting, statistics, and assay optimization and execution is required.
Roles and Responsibilities of the Position*
• Cell Culture Expertise
• Develop robust cell-based assays
• Design, execute, and trouble-shoot experiments
• Experience in the following assay formats: HTRF, ELISA, In-Cell Western, Mesoscale, and Chemiluminescence
• CRISPR and Cloning experience is a plus.
• Perform comprehensive data analysis
• Communicate experimental findings to team members
• Operate, implement and troubleshoot laboratory automation
• Actively engaged in advancing drug discovery programs
• This is a "hands-on" laboratory, based position.

Job Requirements

• BS/MS in biology, biochemistry or related fields
• 2+ years of experience culturing cells and performing cell assays
• A scientific foundation in the understanding and implementation of a wide range of cell-based screening assays and readouts
• Excellent oral and written communication skills including experimental documentation
• Works well with team members daily across functional areas
• Continual learner who works independently and possesses a can-do attitude
• Ability to multi-task and shift priorities rapidly to meet tight deadlines
• Highly organized with exceptional attention to detail
• Proficient in Microsoft Office suite and applications

(Job number: 3923818)